| DATE | MATCH | RESULT |
|---|---|---|
| Aug 14, 2021 | Watford – Aston Villa | 3-2 |
| Aug 21, 2021 | Brighton – Watford | 2-0 |
| Aug 24, 2021 | Watford – C Palace(CC) | 1-0 |
| Aug 29, 2021 | Tottenham – Watford | 1-0 |
| Sep 11, 2021 | Watford – Wolves | 0-2 |
| Sep 18, 2021 | Norwich – Watford | 1-3 |
| Sep 21, 2021 | Watford – Stoke(CC) | 1-3 |
| Sep 25, 2021 | Watford – Newcastle | 1-1 |
| Oct 2, 2021 | Leeds – Watford | 1-0 |
| Oct 16, 2021 | Watford – Liverpool | 0-5 |
| Oct 23, 2021 | Everton – Watford | 2-5 |
| Oct 30, 2021 | Watford – Southampton | 0-1 |
| Nov 7, 2021 | Arsenal – Watford | 1-0 |
| Nov 20, 2021 | Watford – Man Utd | 4-1 |
| Nov 28, 2021 | Leicester – Watford | 4-2 |
| Dec 1, 2021 | Watford – Chelsea | 1-2 |
| Dec 4, 2021 | Watford – Man City | 1-3 |
| Dec 10, 2021 | Brentford – Watford | 2-1 |
| Dec 28, 2021 | Watford – West Ham | 1-4 |
| Jan 1, 2022 | Watford – Tottenham | 0-1 |
| Jan 8, 2022 | Leicester – Watford(FA) | 4-1 |
| Jan 15, 2022 | Newcastle – Watford | 1-1 |
| Jan 21, 2022 | Watford – Norwich | 0-3 |
| Feb 5, 2022 | Burnley – Watford | 0-0 |
| Feb 8, 2022 | West Ham – Watford | 1-0 |
| Feb 12, 2022 | Watford – Brighton | 0-2 |
| Feb 19, 2022 | Aston Villa – Watford | 0-1 |
| Feb 23, 2022 | Watford – C Palace | 1-4 |
| Feb 26, 2022 | Man Utd – Watford | 0-0 |
| Mar 6, 2022 | Watford – Arsenal | 2-3 |
| Mar 10, 2022 | Wolves – Walford | 4-0 |
| Mar 12, 2022 | Southampton – Watford | 1-2 |
| Mar 19, 2022 | Watford – Everton | – |
| Apr 2, 2022 | Liverpool – Watford | – |
| Apr 9, 2022 | Watford – Leeds | – |
| Apr 16, 2022 | Watford – Brentford | – |
| Apr 23, 2022 | Man City – Watford | – |
| Apr 30, 2022 | Watford – Burnley | – |
| May 7, 2022 | C Palace – Watford | – |
| May 15, 2022 | Watford – Leicester | – |
| May 22, 2022 | Chelsea – Watford | – |
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